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Description:Colonic toxicity of administered drugs and chemicals. Additionally, trans-rectal abuse risks anorectal trauma and vascular necrosis with colonic perforation. Previous reports have described inhalational and intravenous routes. Body stuffers, on the other hand, swallow drugs to avoid capture while in possession of drugs. Routes of MA administration are varied, with prior reports of exposure via nasal insufflation, IV administration, ingestion of liquid formulations, and a single case report of intravaginal exposure. A recognized problem with rectal administration is leakage of the mixture after dosing; this is discussed on websites dedicated to the MA use subculture.
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